果糖口服液联合中药小儿康颗粒治疗小儿功能性便秘临床疗效观察

Analysis on the Effects of Lactulose Oral Solution Combined with Xiaoerkang Keli in Treating 70 Cases of Functional Constipation in Children

目的:观察应用乳果糖口服液联合中药小儿康颗粒治疗小儿功能性便秘的疗效,为临床治疗小儿功能性便秘提供更好的治疗方案。方法:将70例功能性便秘患儿随机分为两组,治疗组予乳果糖口服液加中药小儿康颗粒3周,对照组予乳果糖口服液3周,观察两组疗效,并停药4周后随诊。结果:两组患儿便秘均有明显改善,治疗组和对照组的总有效率为94.3%和77.1%,(P<0.05)有显著差异性,停药1月后复发率为6.1%和33.3%,(P<0.05)有显著差异性。结论:乳果糖口服液联合中药小儿康颗粒治疗小儿功能性便秘效果满意,复发率低。

Objective： To investigate the effects of lactulose oral solution combined with Xiaoerkang Keli in treating 70 cases of functional constipation in children. Method： 70 cases of functional constipation infants were divided into two groups. The infants in control group were treated with lactulose oral solution for 3weeks; The infants in treatment group were treated with lactulose oral solution combined with Xiaoerkang Keli for 3 weeks,70 cases were obtained follow-up survey with 4 weeks after drug withdrawal. Result： Compared with control group,a significant increase in overall response rate and a marker decrease in recurernce rate were observed in treatment group（ P〈0.05）. Conclusion： The clinical efficacy of lactulose oral solution combined with Xiaoerkang Keli is better than that of lactulose oral solution in treatment of unctional constipation.