室性期前收缩性心肌病

Premature Ventricular Contraction-induced Cardiomyopathy

频发的室性期前收缩导致心脏结构改变和左心室射血分数下降,称为室性期前收缩性心肌病。消除室性期前收缩后心脏结构和功能可恢复正常。回顾性研究显示,病程长及室性期前收缩负荷高是室性期前收缩性心肌病主要易患因素。其发生机制可能与室性期前收缩发生时心脏无法有效充盈及左右室收缩不同步导致心室腔扩大,心功能下降相关。射频消融术已成为根治室性期前收缩、逆转室性期前收缩性心肌病的唯一方法。

Premature ventricular contraction（ PVC）-induced cardiomyopathy is due to frequent PVCs,which cause left ventricular systolic dysfunction and dilated cardiomyopathy without underlying structural heart disease. The suppression of PVCs can improve impaired left ventricular function. Based on retrospective study,long duration and burden of PVC are mainly risk factors. Radiofrequency catheter ablation is the only radical therapy for PVCs. Moreover,frequent PVCs with impaired left ventricular function is an indication for radiofrequency catheter ablation.