脊柱手术发生下肢静脉血栓的相关危险因素Logistic回归分析

Logistic regression analysis on risk factors of deep vein thrombosis in spinal operation

目的：探讨脊柱手术发生下肢静脉血栓（DVT）的相关危险因素。方法对202例脊柱手术的下肢DVT进行研究，并对发生下肢DVT患者和未发生下肢DVT患者的临床资料进行对比分析，单因素分析采用χ2检验，多因素分析采用多因素非条件Logistic回归进行分析。结果年龄（OR=3.434，95%CI：0.445~2.452）、体重指数（BMI，OR=3.243，95%CI：0.452~2.423）、血清甘油三脂水平（TG，OR=3.535，95%CI：0.353~3.224）、凝血酶原时间（PT，OR=4.545，95%CI：0.463~3.563）是脊柱手术发生下肢DVT形成的危险因素，物理抗凝治疗（OR=4.864，95%CI：0.553~2.563）是脊柱手术发生下肢DVT形成的保护性因素。结论脊柱手术发生下肢DVT是多因素作用的共同结果，应采取积极的预防措施，以避免下肢DVT的形成。

Objective To explore the risk factors for deep vein thrombosis （DVT） in spinal operation. Methods The prevalence of DVT in 202 patients with spinal operation was studied, and the the clinical data of pa-tients with or without lower extremity DVT were analyzed comparatively. Single factor analysis was performed using the chi-squared test, and multivariate analysis was performed using multivariate unconditional Logistic regression analysis. Results Age （OR=3.434, 95%CI：0.445~2.452）, body mass index （BMI, OR=3.243, 95%CI：0.452~2.423）, triglyceride （TG, OR=3.535, 95%CI：0.353~3.224）, prothrombintime （PT, OR=4.545, 95%CI：0.463~3.563） were risk factors of lower extremity DVT in spinal surgery. Physical anticoagulant therapy （OR=4.864, 95%CI： 0.553~2.563） was protective factors for the the formation of lower extremity DVT in spinal surgery. Conclusion Deep vein throm-bosis in spinal operation is the results of many factors. Preoperative active measures should be taken to assess risk fac-tors in order to reduce deep vein thrombosis.