Betatrophin与糖尿病的研究进展

Research progress of betatrophin and diabetes

补充胰岛再生β细胞的数量被认为是一个潜在治疗糖尿病的一个靶点。最近研究证实胰岛再生激素(Betatrophin)具有高效、显著提高β细胞增殖的能力,并且可显著提高糖耐受的能力。Betatrophin的发现为糖尿病的治疗提供了新型的治疗机会。以往的研究主要集中于它的特征和功能以及胰腺β细胞的增殖情况,本文则对Betatrophin与糖尿病的最新进展进行总结。

Replenishing the insulin-producing/β-cells is considered as a potential cure method for diabetes. A recent study identified a secreted protein, betatrophin, could potently and significantly improve the ability of beta cell proliferation, and can significantly improve the sugar tolerance ability. The discovery of betatrophin provided a new type of therapy for the treatment of diabetes. The previous studies mainly focused on its features and functions as well as the proliferation of the pancreatic beta ceils. In this article, the research progress of betatrophin and diabetes were summarized