116例HIV/AIDS病例5年随访期生存情况调查

Investigation of survival condition of 116HIV/AIDS patients in 5-year follow-up period

目的了解HIV/AIDS病例生存状况,为开展艾滋病自愿咨询及关怀服务提供依据。方法收集116例HIV/AIDS病例相关资料,并开展为期60个月的随访,采用生存分析方法,分析病例的生存情况。结果 60个月的随访期内死亡25例,累积生存率为78.4%,平均生存时间为(50.2±1.9)月;其中12个月随访期内累计死亡14例,累积生存率为87.9%。接受抗病毒治疗组累积生存率为92.6%,未接受治疗组累积生存率为66.1%,差异有统计学意义(χ2=14.752,P=0.000)。主要死因为艾滋病相关疾病和吸毒过量。结论确诊为HIV阳性后12个月内病例死亡风险较高,接受抗病毒治疗者可能更易存活。应通过宣传、转介等手段积极引导需要治疗的病人接受抗病毒治疗。

Objective To investigate survival condition of HIV/AIDS patients,to provide basis for carrying out volunteer consultation and patient-care services.Methods Information of 116HIV/AIDS patients was collected,60-month period of follow-up management was conducted.Survival analysis method was used to analyze survival condition of patients.Results In 60-month follow-up period,a total of 25 patients died,resulting the cumulative survival rate of 78.4% and the average survival time of（50.2±1.9）months.In the first 12-month period,14 patients died,resulting the cumulative survival rate of 87.9%.The cumulative survival rate of group under antiretvoviral therapy was 92.6%,which was higher than the rate of 66.1% for untreated group,with significant difference（χ2=14.752,P=0.000）.AIDS related diseases and overdose were major death causes.Conclusion Death risk is high in the first 12-month period upon diagnosis of HIV infection.Patients under antiretvoviral therapy have more chance to survive.Advocacy,referral and other means should be taken to actively guide patients to receive antiretvoviral therapy.