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类风湿关节炎早发动脉粥样硬化机制的研究进展 被引量：5

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摘要 类风湿关节炎（RA）是一种累及外周关节为主的慢性、系统性、炎症性自身免疫性疾病。全身和关节滑膜合成的促炎细胞因子如肿瘤坏死因子-α（TNF-α）、白细胞介素6（IL-6）、IL-17等在关节损害和终末器官损害中起着关键作用。RA患者易于并发动脉粥样硬化,心肌梗死和卒中的风险显著增加。
作者 常文静 蔡辉
机构地区 南京军区南京总医院中西医结合科
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2015年第3期426-428,432,共4页 Chinese Journal of Immunology
关键词 动脉粥样硬化 类风湿关节炎 肿瘤坏死因子-α 自身免疫性疾病 促炎细胞因子 TNF-α 白细胞介素 IL-17
分类号 R593.3 [医药卫生—内科学]
  • 相关文献

参考文献31

  • 1Avina-Zubieta JA, Choi HK, Sadatsafavi M, et al. Risk of cardiovascular mortality in patients with rheumatoid arthritis: a meta-analysis of observational studies [ J ]. Arthritis Rheum, 2008, 59 ( 12 ) : 1690-1697.
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  • 5李鸿斌,白莉,吴庆军,张煊,张奉春.类风湿关节炎患者合并心脑血管病的危险性分析[J].中华医学杂志,2006,86(25):1769-1773. 被引量：10
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二级参考文献33

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共引文献10

同被引文献43

引证文献5

二级引证文献50

中国免疫学杂志
2015年 第3期

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