摘要
Hepatocellular carcinoma(HCC) is the fifth most common malignancy and the third cause of tumor associated deaths worldwide. HCC incidence rates are increasing in many parts of the world including developing and developed countries. Potentially curative treatments for HCC are resection and liver transplantation, but these are only suitable for patients with small tumors, meeting strict pre-defined criteria, or well-compensated liver disease. Early diagnosis of HCCcan be achieved by surveillance of at-risk populations. For patients with non-resectable disease treatments modalities include loco-ablative and systemic therapies. In this review we focus on treatment options in HCC and their allocation. Although significant research is in progress, to this date, the results are unsatisfactory with limited long-term survival. In the fight against this deadly disease, there is still a long way to go.
Hepatocellular carcinoma （HCC） is the fifth mostcommon malignancy and the third cause of tumorassociated deaths worldwide. HCC incidence ratesare increasing in many parts of the world includingdeveloping and developed countries. Potentiallycurative treatments for HCC are resection and livertransplantation, but these are only suitable for patientswith small tumors, meeting strict pre-defined criteria, orwell-compensated liver disease. Early diagnosis of HCCcan be achieved by surveillance of at-risk populations.For patients with non-resectable disease treatmentsmodalities include loco-ablative and systemic therapies.In this review we focus on treatment options in HCCand their allocation. Although significant research is inprogress, to this date, the results are unsatisfactorywith limited long-term survival. In the fight against thisdeadly disease, there is still a long way to go.
