应用血管回声跟踪技术在评价吸烟者颈动脉弹性功能的研究

Evaluation of Carotid Artery Elasticity in Smokers Using Vascular Echo-tracking Technique

目的应用血管回声跟踪技术(ET)评价吸烟者颈动脉血管壁弹性,以探讨吸烟行为对颈动脉血管弹性的影响。方法选取体检结果正常的男性吸烟者129例,非吸烟者46例(A组),按吸烟指数将吸烟者分为3组,B组(0<BI≤200),C组(200<BI≤400)和D组(BI>400),应用ET技术检测各组颈动脉内中膜厚度(IMT)、收缩期血管内径(Ds)和舒张期血管内径(Dd),并计算硬度指数(β)、压力应变弹性系数(Ep)、动脉顺应性(AC)及单点脉搏波传导速度(PWVβ),以比较不同吸烟指数组间的颈总动脉弹性。结果对照组及各吸烟组间IMT、Ds及Dd差异均无统计学意义,4组β、Ep、AC、及PWVβ差异有统计学意义(P<0.01),A组与B组比较差异无统计学意义,3个吸烟组中任意两组比较差异均有统计学意义(P<0.01)。β、Ep及PWVβ均随吸烟指数的增加而增高,而AC随吸烟指数的增加而减低。结论 ET技术能早期检测到吸烟者动脉弹性功能改变,血管弹性功能变化要早于形态学变化。

Objective To investigate smoking behavior impacting on carotid artery elasticity ,Echo-track-ing technique （ET ） evaluation of carotid artery w all elasticity in smokers w as used .Methods 1 2 9 cases of male smokers and 46 cases of non-smokers were selected when their physical examination results were normal ,and the later was as group A .According to the index of smoking ,1 2 9 smokers were divided into three groups ,group B（0 ≤BI≤2 0 0 ） ,group C（2 0 0 〈BI≤4 0 0 ）and group D（BI〉4 0 0 ） .The carotid intima-media thickness （IM T ）、systolic diameter （Ds） and diastolic diameter （Dd） were detected using ET technology ,and the stiffness index （beta） 、pressure strain elastic coefficient （Ep）、arterial compliance （AC） and single pulse wave velocity （PWVβ） were calculated in each group .Common carotid artery elasticity in different smoking index groups were com-pared .Result There were no significant differences in IM T、Ds and Dd between control Group （A）and smok-ing groups ,but the statistical significance different of β,Ep ,AC ,and PWV βbetween 4 groups existed（ P〈0 .0 1 ） ,Compared A with B group ,there was no statistical difference ,differences between in 2 random groups of 3 smoking groups was statistically significant（P〈0 .01 ）.β、Ep、PWVβwere increased and AC decreased with the smoking index increase .Conclusion ET can detect the change of smokers artery elastic function earlier .T he changes of blood vessel elasticity function is earlier than morphological .