期刊文献+

突触功能状态与血管性认知障碍研究进展 被引量:4

下载PDF
导出
摘要 血管性认知障碍(vascular cognitive impairment,VCI)是指脑血管病危险因素(如高血压、糖尿病和高血脂等)、明显(如脑梗塞和脑出血)或不明显的脑血管病(如白质疏松和慢性脑缺血)引起的从轻度认知功能障碍到痴呆的一大类综合征。VCI的发病率呈逐年上升趋势,其发病率仅次于Alzheimer病(Alzheimer disease,AD),是引起老年期痴呆、
出处 《中风与神经疾病杂志》 CAS 北大核心 2015年第3期275-278,共4页 Journal of Apoplexy and Nervous Diseases
基金 成都军区医学科学技术研究"十二五"计划研究项目(No.C12045) 成都军区总医院重点研究项目(No.2013YG-A006)
  • 相关文献

参考文献35

  • 1Atwood HL,Wojtowicz JM.Silent synapses in neural plasticity:current evidence[J].Learn Mem,1999,6(6):542-571.
  • 2Hanse E,Seth H,Riebe I.AMPA-silent synapses in brain development and pathology[J].Nat Rev Neurosci,2013,14(12):839-850.
  • 3Zhou C,Lippman JJ,Sun H,et al.Hypoxia-induced neonatal seizures diminish silent synapses and long-term potentiation in hippocampal CA1neurons[J].J Neurosci,2011,31(50):18211-18222.
  • 4Sametsky EA,Disterhoft JF,Geinisman Y,et al.Synaptic strength and postsynaptically silent synapses through advanced aging in rat hippocampal CA1pyramidal neurons[J].Neurobiol Aging,2010,31(5):813-825.
  • 5Nusser Z,Lujan R,Laube G,et al.Cell type and pathway dependence of synaptic AMPA receptor number and variability in the hippocampus[J].Neuron,1998,21(3):545-559.
  • 6Liao D,Zhang X,O’Brien R,et al.Regulation of morphological postsynaptic silent synapses in developing hippocampal neurons[J].Nat Neurosci,1999,2(1):37-43.
  • 7Kerchner GA,Nicoll RA.Silent synapses and the emergence of a postsynaptic mechanism for LTP[J].Nat Rev Neurosci,2008,9(11):813-825.
  • 8Liao D,Scannevin RH,Huganir R.Activation of silent synapses by rapid activity-dependent synaptic recruitment of AMPA receptors[J].J Neurosci,2001,21(16):6008-6017.
  • 9Petralia RS,Esteban JA,Wang YX,et al.Selective acquisition of AMPA receptors over postnatal development suggests a molecular basis for silent synapses[J].Nat Neurosci,1999,2(1):31-36.
  • 10Gomperts SN,Rao A,Craig AM,et al.Postsynaptically silent synapses in single neuron cultures[J].Neuron,1998,21(6):1443-1451.

同被引文献34

引证文献4

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部