井下作业工人25羟基维生素D水平测定及影响因素调查分析

Underground workers 25-hydroxy vitamin D level determination and influence factors investigation analysis

目的：通过对煤矿井下工人进行调查，分析井下工人维生素D缺乏及影响因素的分析，以期为更好地制定防治措施提供理论依据。方法：以参加2013-2014年度职工查体的956名在职井下职工为研究对象（观察组），同期健康查体者103名（对照组）均抽取清晨空腹静脉血，用酶联免疫定量法检测血清25羟基维生素D水平，并以Spearman等级相关法分析其相关性。结果：观察组和对照组血清25羟基维生素D水平分别为（44.67±31.67）、（52.32±25.54）nmol/L（P〈0.05），观察组伴2型糖尿病和非2型糖尿病者分别为（38.46±20.25）、（46.17±31.05），2型糖尿病者显著低于非2型糖尿病者和对照组（P均〈0.05），观察组血清25羟基维生素D水平与年龄、工龄及是否伴有2型糖尿病等有关，但与吸烟、饮酒等无明显相关性，与肥胖及高血压的相关性须进一步探讨。结论：井下工人血清维生素D水平普遍偏低，应该是紫外线照射时间短、摄入少等因素共同作用的结果，应注意进一步对井下工人加强健康教育，关注井下工人的维生素D营养状况和骨质状态并及时干预。

Objective：To evaluate the vitamin D nutritional status of coal miners,in order to better provide theoretical basis for prevention and control measures Methods：To participate in the 2013-2014 year worker on examination of 956 working underground worker （observation group） as the research object, the same kindergarden is 103 （control group） were extracted in the morning fasting venous blood, enzyme league immune quantitative method to detect serum 25-hydroxyitamin D levels, and Spearman rank correlation method was used to analyze the correlation.Results：Observation group and control group 25 hydroxy serum vitamin D levels（44.67±31.67）and（52.32±25.54）nmol/L（P〈0.05）respectively,which of the T2DM and non-T2DM in the observed group were（38.46±20.25）and（46.17±31.05）respectively,serum 25-OH-D of theT2DM were significantly lower than that of then on-T2D and the control group （all P〈0. 05）.the serum 25-OH-D level in observed group is associated with age,length of service and whether with T2DM,but was not related significantly with smoking, drinking and the history of fractures. Conclusions：Underground workers Serum vitamin D level is relative low, should be uv irradiation time is short, eat less factors such as the result of joint action, attention should be paid to further strengthen the health education of underground workers, underground workers vitamin D nutritional status and bone status and timely intervention.