康莱特注射液对改善癌症晚期患者生存质量的临床观察

Clinical observation of Kanglaite injection in improving life quality of patients with advanced cancer

目的对癌症晚期患者应用康莱特注射液,观察其对改善患者生存质量的作用。方法 50例癌症晚期患者应用康莱特注射液200 ml,静脉滴注,1次/d,21 d为1个疗程,应用2个疗程后观察患者情况及Karnofsky评分。结果治疗后患者食欲比治疗前有明显改善(P<0.01);体重与治疗前比较均有不同程度的增加,差异有统计学意义(P<0.01);疼痛有不同程度的减轻,疼痛缓解率为56%,Karnofsky评分60分以上者由44%提高到64%,差异有统计学意义(P<0.01)。结论康莱特注射液可以从改善食欲、增加体重、缓解疼痛、提高Karnofsky评分几个方面提高晚期癌症患者的生存质量。

Objective To observe the effect of Kanglaite injection in improving life quality of patients with advanced cancer. Methods A total of 50 patients with advanced cancer received 200 ml of Kanglaite injection through intravenous drip by 1 time/d for 21 d as 1 course. After 2 courses of treatment, patients＇ condition and Karnofsky scores were observed. Results Patients＇ appetite was obviously improved after treatment, compared with that before treatment（P〈0.01）, and their weight was also improved by different range, and the difference had statistical significance（P〈0.01）. Their pain was relieved by different degree, and the total relief rate was 56%, and patients with Karnofsky score higher than 60 points increased from 44% to 64%. The difference had statistical significance（P〈0.01）. Conclusion Kanglaite injection can improve the life quality of patients with advanced tumor in the respects as improving appetite, weight, karnofsky score, and relieving pain.