渐进性咬合紊乱对幼年兔颞下颌关节的影响

Influence of gradually induced occlusal disorder on temporomandibular joint in young rabbit

目的 :探讨幼年期的渐进性咬合紊乱对颞下颌关节的影响。方法 :18只 7周龄的新西兰白兔 ,分成实验组和对照组。采用固定矫治技术造成实验组渐进性咬合紊乱 ,在 1、2、3月对TMJ进行组织学检查。结果 :实验组变化主要在下颌髁状突上 ,1月组表现为髁突的中外侧层次结构紊乱。 2月组退行性改变和修复反应并存 ,并观察到两侧髁突与关节盘粘连。 3月组层次结构基本恢复 ,软骨厚度相对较薄。结论

Objective:To investigate the influence of gradually induced occlusion disorder on temporomandibular joint in young rabbits. Methods: The upper first premolar on one side and the lower first premolar on the other side of 18 New Zealand white rabbits at the age of 7 months, were pulled forward with the orthodontic string, making them inclined medially to the anterior intrinsic space. The TMJs were removed 1,2 and 3 months respectively after set up and observed histologically. Results: In the 1 month group,TMJs exhibited regressive remodeling on the lateral side. In the 2 month group,the joints simultaneously showed progressive remodeling and degenerative changes.The TMJ condyle cartilage were thinner than the controls.Conclusion: Gradually induced occlusion disorders can lead TMJ degenerative changes in young rabbit.