多烯磷脂酰胆碱治疗酒精性肝病的临床观察

Clinical Observation of Polyene Phosphatidylcholine on Alcoholic Liver Disease

目的观察多烯磷脂酰胆碱注射液治疗酒精性肝病的疗效。方法将60例酒精性肝病的患者给予多烯磷脂酰胆碱注射液465毫克溶于5%葡萄糖注射液250毫升中静脉滴注,每日1次,疗程4周。观察临床症状、体征、肝功、血脂、肝脏超声影像学及药物不良反应的发生。结果临床症状、体征、肝功得到明显的恢复,降血脂显著,而且能够提高肝脏超声影像学的复常率,不良反应发生率低。结论多烯磷脂酰胆碱注射液是治疗酒精性肝病的有效药物之一。

ObjectiveTo observe the effect Polyene Phosphatidylcholine Injection treatment of alcoholic liver disease.Methods 60 patients with alcoholic liver disease patients were given Polyene Phosphatidylcholine Injection 465 mg dissolved in 250 ml intravenously 5% Glucose Injection, 1 times a day, for 4 weeks. Observation on clinical symptoms, signs, liver function, blood lipids, liver ultrasound imaging and drug adverse reaction.Results The clinical symptoms, signs, liver function obviously recovery, signiifcantly reducing blood lipid, but also can improve the liver ultrasound imaging of the recovery rate, low incidence of adverse reactions. ConclusionPolyene Phosphatidylcholine Injection is one of the most effective drugs for the treatment of alcoholic liver disease.