雷贝拉唑联合奥美拉唑治疗老年反流性食管炎临床观察

Clinical Observation on Rabeprazole Combined With Omeprazole in Treatment of Elderly Patients With Reflux Esophagitis

目的：探讨雷贝拉唑联合奥美拉唑治疗老年性反流性食管炎的临床疗效。方法选取于2013年7月～2014年9月在我院接受治疗的46例老年性反流性食管炎患者随机分成对照组和治疗组，对照组患者给予雷贝拉唑治疗，治疗组患者给予雷贝拉唑联合奥美拉唑治疗，对两组患者的治疗效果进行对比。结果对照组的治疗总有效率为60.9%，治疗组的治疗总有效率为82.6%，治疗组患者的治疗总有效率明显高于对照组，差异显著，治疗有统计学意义（P＜0.05）。结论雷贝拉唑联合奥美拉唑治疗老年性反流性食管炎的临床疗效显著，能够快速缓解患者的临床症状并且不良发应情况较少，对老年性反流性食管炎有着重要的临床应用价值。

ObjectiveTo investigate clinical efficacy of rabeprazole combined with omeprazole in treatment of elderly patients with reflux esophagitis.MethodsChoose 46 elderly patients with reflux esophagitis who are treated in hospital from July 2013 to September 2014 and separate them into control group and study groupat random; patients in control group are given rabeprazole treatment only; while patients in study group are given rabeprazole combined with omeprazole treatment, and then observe and compare treatment efficacy in these two groups. ResultsTreatment efifcacy in control group is 60.9%; while treatment efifcacy in study group is up to 82.6% , which is much higher than that in control group; there is differential between study group and control group and such a differential has statistic value （P〈0.05）.Conclusion Rabeprazole combined with omeprazole is of efficacy in treatment of elderly patients with reflux esophagitis; it is conducive to relieving patients’ illness symptoms quickly with fewer side effects, which is of great clinical application signiifcance in treatment of elderly patients with relfux esophagitis..