垂体后叶素联合硝酸甘油治疗肺结核大咯血的临床观察

ituitrin Combined Nitroglycerin Clinical Observation for the Treatment of Pulmonary Tuberculosis Big Hemoptysis

目的探讨垂体后叶素联合硝酸甘油治疗肺结核大咯血的临床观察。方法将2013年7月～2014年7月在我院传染病科治疗的40例肺结核大咯血患者随机分为两组，对照组采用常规治疗＋垂体后叶素的方法，观察组在此基础上辅助硝酸甘油治疗，比较两组患者的治疗效果、止血时间、出血量、不良反应等。结果观察组治疗有效率95%，明显高于对照组75%，差异有统计学意义（P＜0.05）；观察组治疗后止血时间、出血量均少于对照组，差异有统计学意义（P＜0.05）；观察组腹痛、腹泻、心悸、胸闷等不良反应发生率明显低于对照组，差异有统计学意义（P＜0.05）。结论垂体后叶素联合硝酸甘油治疗肺结核大咯血疗效显著，止血速度快，不良反应少。

ObjectiveTo study the pituitrin combined nitroglycerin clinical observation for the treatment of pulmonary tuberculosis big hemoptysis. Methods July 2013-July 2014 in our hospital infectious diseases treatment of 40 patients with pulmonary tuberculosis big hemoptysis were randomly divided into two groups, control group adopts the method of conventional treatment＋pituitrin, the observation group based on the auxiliary nitroglycerin treatment, compare the curative effect of two groups of patients, the bleeding time, blood loss, adverse reactions, etc.Results Observation group treatment effective rate was 95%, higher than the control group was 75%, the difference was statistically signiifcant （P〈0.05）; The bleeding time and blood loss after treatment observation group were less than the control group, the difference was statistically signiifcant （P〈0.05）; Observation group of abdominal pain, diarrhea, palpitation, chest tightness and other adverse reaction rates signiifcantly lower than the control group, the difference was statistically significant （P〈0.05）.Conclusion Pituitrin combined nitroglycerin pulmonary tuberculosis big hemoptysis with obvious therapeutic effect, fast hemostasis, less adverse reaction.