摘要
Dear Editor, Among many of biophysical methods, 19F NMR spectros- copy has emerged as a powerful tool for characterizing protein structure, dynamics and function properties due to high intrinsic sensitivities of fluorine, 100% natural abundance of the NMR-active spin, the absence of any natural background in cells, and exquisite sensitivities of 19F chemical shift to environment （Shi et al., 2011; Shi et al.,
Dear Editor, Among many of biophysical methods, 19F NMR spectros- copy has emerged as a powerful tool for characterizing protein structure, dynamics and function properties due to high intrinsic sensitivities of fluorine, 100% natural abundance of the NMR-active spin, the absence of any natural background in cells, and exquisite sensitivities of 19F chemical shift to environment （Shi et al., 2011; Shi et al.,
