HRCT在肺单发性磨玻璃样病灶鉴别诊断中的价值分析

Application of high resolution computed tomography in pathological diagnosis of solitary pulmonary ground-glass opacity

目的:探讨肺单发性磨玻璃样病灶(solitary pulmonary ground glass opacity,sp GGO)的计算机断层扫描(computed tomography,CT)影像学表现与其良恶性的关系。方法:收集196例手术治疗的sp G G O患者的临床资料。回顾性分析病灶的CT影像学特征,包括肿瘤大小、内部结构(空泡征、支气管充气征)、毛刺征、病变分叶征、血管集束征、胸膜凹陷征。对照CT与病理结果,总结影像学特征与GGO性质的关系。结果:良恶性GGO患者的CT空泡征、支气管充气征表现的差异无统计学意义(P>0.05)。在肿瘤的大小、分叶征、毛刺征、胸膜凹陷征、血管集束征的表现方面,其差异具有统计学意义(P<0.05)。结论:GGO的影像学特征上,直径越大其恶性可能性越大,病变的分叶、毛刺征、胸膜凹陷征和血管集束征可作为恶性GGO的特征。

Objective： To investigate the relationship of computed tomography （CT） findings with benign or malignant features of solitary pulmonary ground-glass opacity （spGGO）. Methods： CT characteristics including tumor size, internal characteristics （ovule sign, air bronchograms）, lobulationj burr, pleural indentation and closing the vessel convergence sign and pathological diagnosis were retrospectively analyzed with 196 patients of solitary pulmonary ground-glass opacity that was confirmed by histopathology. The data were analyzed to summarize the relationship between CT findings and GGO features. Results： The existence of ovule sign and air-bronchogram of the lesions were no statistically significant differences between benign and malignant GGOs （P〉0.05）. Lobulation, burr, pleural indentation and closing the vessel convergence sign were significantly different between benign and malignant GGOs （P〈0.05）. Conclusion： The longer the diameter of GGO, the higher the possibility of malignancy. CT characteristics including lobulation, burr, pleural indentation and closing the vessel convergence sign can be used as the specific signs of malignant GGO.