女性生殖道黏膜的先天性免疫研究进展

Progress in the research on innate immunity at mucosal surfaces of the female reproductive tract

黏膜广泛分布于机体的肠道、泌尿生殖道及呼吸道的表面,它们形成一道物理和免疫屏障,抵御入侵的各种病原微生物。有关黏膜免疫的研究多集中在肠道和呼吸道,而关于女性生殖道黏膜免疫的研究相对较少。本文就女性生殖道先天性黏膜免疫系统的组成和机制作一简要综述。

Including in the gastrointestinal, urogenital, and respiratory tracts, mucosal surfaces provide a physical and immunological barrier against a variety of pathogens. Many studies have been focused on gastrointestinal and respiratory mucosal sites. However, there has been little investigation of reproductive mucosal sites. The goal of this review is to focus on the diverse components and mechanisms of the innate immune systems throughout the female reproductive tract.