胃食管反流病药物治疗110例

Gastroesophageal Reflux Disease 110 Cases of Drug Treatment

目的探讨兰索拉唑联合蒲元和胃胶囊治疗胃食管反流病的疗效。方法治疗组给予兰索拉唑肠溶片、蒲元和胃胶囊口服;对照组给予兰索拉唑肠溶片和吗丁啉口服,疗程均为6周。观察临床疗效、胃镜下改变、不良反应和复发率。结果两组均能有效缓解食管反流病患者的症状,治疗组总有效率96.3%,对照组的81.8%,两组比较,P<0.05。内镜下表现治疗组总有效率83.3%,对照组的64.7%(P<0.05)。经治疗两个月后随访,治疗组能够很好的控制复发。两组均没有发现明显的毒副作用。结论兰索拉唑、蒲元和胃胶囊治疗胃食管反流病疗效满意,复发率低,值得临床推广。

Objective To study the lansoprazole joint PuYuanHeWei capsule curative effect for the treatment of gas- troesophageal reflux disease. Methods The treatment group given LAN sola azole joint PuYuanHe stomach enteric- coated metformin hydrochloride capsules of oral. The control group given lansoprazole enteric-coated metformin hydro- chloride and ding Lin oral, a course of 6 weeks. To observe the clinical curative effect, change under gastroscope, adverse reactions and the recurrence rate. Results Both groups can effectively alleviate the symptoms of GERD patients, treat- ment group total effectiveness 96.3%, that of control group is 81.8% （P〈0.05）. Endoscopic treatment group total effective- ness 83.3%, that of control group is 64.7%（P〈0.05）. After follow-up after 2 months of treatment, the treatment group can good control the recurrence. The side effects of two groups were not significant. Conclusion Lansoprazole joint PuYuan- HeWei capsule in the treatment of gastroesophageal reflux disease satisfied curative effect, the recurrence rate is low. It is worth of clinical promotion.