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神经病理性疼痛机制的研究进展 被引量：2

Progress of pathogenesis of neuropathic pain
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摘要 神经病理性疼痛是由躯体感觉神经系统的损伤或疾病所直接引起的疼痛.疼痛症状包括自发性疼痛、痛觉过敏、痛觉超敏等.单纯的镇痛药物很难满意控制疼痛,如何有效控制疼痛是临床治疗的难点,针对神经病理性疼痛的机制来对患者进行治疗是目前研究热点.该文就该病发病机制的研究进展进行综述. Neuropathic pain arises as a direct consequence of a lesion or disease affects the somatosensory.Its symptoms include spontaneous,hyperalgesia and allodynia pain.Pain management is not satisfied through merely analgesics.To manage pain effectively is difficult in clinic.The paper is to review the progress of the mechanism of neuropathic pain.
作者 王菲菲 赵平 韩光
机构地区 中国医科大学附属盛京医院麻醉科
出处 《国际儿科学杂志》 2015年第2期138-141,共4页 International Journal of Pediatrics
关键词 神经病理性疼痛 病理生理学 痛觉过敏 痛觉超敏 中枢敏感化 Neuropathic pain Pathophysiology Hyperalgesia Allodynia Central sensitization
分类号 R741 [医药卫生—神经病学与精神病学]
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参考文献23

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二级参考文献10

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共引文献10

同被引文献24

  • 1张飞娥,张励才,贾晋太,徐美蓉,曹君利,宋学军,曾因明.神经病理性疼痛大鼠鞘内注射SB203580的镇痛作用[J].中华麻醉学杂志,2006,26(4):356-359. 被引量：7
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  • 10Kwon SG, Roh DH, Yoon SY, et al. Blockade of peripheral P2Y1 receptors prevents the induction of thermal hyperalgesia via modulation of TRPV1 expre- ssion in carrageenan-induced inflammatory pain rats: Involvement of p38 MAPK phosphorylation in DRGs. Neuropharmacology, 2014, 79:368 - 379.

引证文献2

二级引证文献13

国际儿科学杂志
2015年 第2期

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