1821例呼吸道病原体感染种类及特点

The infection types and characteristics of 1821 respiratory tract pathogens cases

目的：分析常见呼吸道感染的病原体及其感染特点。方法：回顾性分析昆明医科大学第一附属医院2013年1～12月住院患者中进行过呼吸道九项病原体IgM抗体检测的1821例患者。采用间接免疫荧光法检测患者血清中的嗜肺军团菌（LPN－1）、肺炎支原体（MP）、Q热立克次体（COX）、肺炎衣原体（CP）、腺病毒（ADV）、呼吸道合胞病毒（RSV）、甲型流感病毒（FluA）、乙型流感病毒（FluB）和副流感病毒1、2和3型（PIV）等9种呼吸道感染病原体的IgM抗体。分析在不同性别、年龄段、季度情况下呼吸道病原体感染情况。结果：1821例标本中，男性患者1102例，女性患者719例。共检出IgM抗体阳性843例（46．29％），其中，检出单一病原体感染阳性标本433例，病原体混合感染阳性标本410例。住院科室中，儿科受检例数最高，为1291例，其中检出IgM抗体阳性例数为674例，阳性率为52．21％。14岁以下儿童中，≤1岁组病原体检出率为25．93％，1～14岁组病原体检出率为67．41％；14岁以上人群中，14～20岁组病原体检出率为35．71％，20～60岁组病原体检出率为39．26％，≥60岁组病原体检出率为19．31％。不同季度呼吸道病原体感染情况不同。第一季度病原体检出率较高（59．34％），第二季度病原体检出率较低（34．15％）。结论：呼吸道病原体感染率与年龄、性别、季节有关；儿童是呼吸道病原体的主要易感人群，肺炎支原体的感染是其急性呼吸道感染中的主要病原体之一；采用间接免疫荧光法快速检测人血清中9种呼吸道感染主要病原体的IgM抗体，可为临床的诊断和治疗提供重要的参考依据。

Objective To understand the common respiratory infection in the population of infection of pathogens and their charac-teristics.Methods retrospective analysis of first affiliated hospital of Kunming Medical University 2013 in-patients respiratory patho-gens in 1821 of the nine test cases.Used indirect immune fluorescent law detection patients serum in the of addicted to lung Regiment bacteria （LPN-1 ）,and pneumonia support original body （MP）,and Q hot rickettsia （COX）,and pneumonia clothing original body （CP）,and glands virus （ADV）,and respiratory collection cell virus （RSV）,and swine influenza virus （FluA）,and b type influenza virus （FluB）and Deputy influenza virus 1 ,and 2 and 3 type （PIV）,9 species respiratory infection disease original body of IgM anti-body.Analysis in different sections,sex,age,season case infection of human pathogens.Results 1821 in specimens from patients, male1102patients,719casesoffemalepatients.Totalof843casesofpositivedetectionofIgMantibody（46.29%）,ofwhich,chec-king out a single positive specimens 433 cases of pathogen infections,infection with pathogens positive specimens in 410 cases.Inpa-tient,pediatric pathogens highest tested,1291 cases,of which 674 cases of detection of IgMantibody positive cases,the positive rate for 52. 21%.In children under the age of 14,pathogenic examination rate ≤ 1 year old group is 25. 93%,1 -14sui group of patho-genic examination rate is 67. 41%;among people over the age of 16,pathogenic examination rate for 35. 71%the 14-20sui group,20-60sui group of pathogenic examination rate for pathogenic examination 39. 26%,〉60 age group rate for 19. 31%.Respiratory tract pathogens infection in different seasons on a regular basis.Pathogenic examination rate for the first quarter was higher （57%）in the fourth quarter,lower rates of pathogenic examination （7. 6%）.Conclusionspopulation respiratory tract pathogens infection associated with age,sex,season.children is the main respiratory pathogens susceptible populations,Mycoplasma pneumonia infection in pediatric patients with acute upper respiratory tract infection is the important one of the pathogens.indirect immuno-fluorescence assay for rapid detection of 9 kinds of main pathogens of respiratory tract in human serum IgMantibodies for clinical diagnosis and treatment provide an important frame of reference.