摘要
目的探讨辅助生殖技术中中重度卵巢过度刺激综合征(OHSS)的临床特征、高危因素、妊娠结局。方法回顾性分析我院生殖中心2010年4月至2014年4月间接受IVF/ICSI-ET治疗的483个周期,选择发生中重度OHSS的26个周期为OHSS组,与随机筛选同期接受IVF/ICSI-ET治疗时未发生OHSS的患者30个周期作为对照组,对比研究两者的相关指标。结果 OHSS组年龄轻,多囊卵巢综合征(PCOS)患者比例大,注射HCG日E2水平高,Gn总用量多,HCG日≥12 mm的卵泡数多,临床妊娠率高,两组比较有显著性差异(P<0.05)。结论促排卵过程中应充分预测卵巢反应性,个体化选择促排卵方案,减少卵泡的募集,预防和降低中重度OHSS的发生率,提供IVF安全性。
Objective To explore the clinical characteristics ,risk factor ,pregnancy outcomes of moderate -severe ovarian hyperstimulation syndrome （OHSS） in assisted reproductive technique .Method From April 2 0 1 0 to April 2 0 1 4 ,4 8 3 cycles of IVF/ICSI-ET were analyzed retrospectively .2 6 cycles took place in the moderate-severe OHSS patients as OHSS groups ,3 0 cycles in non -OHSS as contol group by random .We compared pa-tient ,s characteristics and correlative parameters .Results The age ,the total doses of Gn ,the serum E2 levels on the day of hCG administration ,ulrasound monitoring follicle number greater than 1 2 mm in diameter on the day of hCG were significantly different between the OHSS group and the non -OHSS group（P〈0 .05 ） .Con-clusion We should predict the ovarian reactivity fully ,choose ovulation induction programs individualized ,re-duce the raising of follicles to prevent the occurrence of OHSS .
出处
《内蒙古医学杂志》
2015年第3期257-260,共4页
Inner Mongolia Medical Journal
