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美托洛尔治疗慢性充血性心力衰竭疗效观察 被引量:15

Clinical efficacy of Metoprolol for chronic congestive heart failure
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摘要 目的探讨美托洛尔治疗慢性充血性心力衰竭的临床疗效。方法回顾性分析慢性心衰患者60例的临床资料。28例患者采用常规治疗为对照组,32例患者在常规治疗的基础上给予美托洛尔治疗,为研究组。比较两组患者的临床疗效。结果治疗后,研究组和对照组心功能分级均有显著改善(P<0.05),但研究组改善较对照组更明显(P<0.05)。与治疗前比较,两组CI、CO、LCW显著升高,BNP显著下降(P<0.05)。治疗后两组间比较,研究组CI、CO、LCW显著高于对照,BNP显著低于对照组(P<0.05)。结论在常规治疗基础上加美托洛尔治疗慢性充血性心力衰竭能够显著改善临床疗效。 Objective To discuss clinical efficacy of Metoprolol for chronic congestive heart failure. Methods Clinical data of 60 cases with chronic congestive heart failure were retrospectively analyzed.Twenty-eight cases were treated by normal treatment as control group,and 32 cases were treated by Metoprolol based on normal treatment as study group.Clinical efficacy of two groups was compared. Results After treatment,NYHA classification of two groups improved apparently(P〈0.05),but that of study group improved more than control group(P〈0.05).Compared with before treatment,CI,CO,LCW of two groups increased and BNP decreased apparently (P〈0.05).After treatment,levels of CI,CO,LCW of study group were higher than control group and BNP was lower than control group(P 〈 0.05). Conclusion Metoprolol based on normal treatment for chronic congestive heart failure can improve clinical efficacy.
作者 郭杏花
出处 《中国医药科学》 2015年第3期111-113,共3页 China Medicine And Pharmacy
关键词 慢性充血性心力衰竭 美托洛尔 Β受体阻滞剂 Chronic congestive heart failure Metoprolol β-blockers
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