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两性霉素B治疗白血病合并侵袭性真菌感染的临床疗效分析 被引量:1

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摘要 目的探讨两性霉素B在治疗白血病合并侵袭性真菌感染的疗效。方法选取151例就诊于我院的白血病合并真菌感染患者151例,分为观察组和对照组,分别给予两性霉素B和氟康唑治疗,观察其疗效及不良反应。结果观察组和对照组的总有效率分别为93.4%和77.3%,两组相比,差异具有统计学意义(P〈0.05)。治疗过程中两组患者未出现严重不良反应,较轻的不良反应包括肝功能异常,观察组和对照组发生率分别为22.4%和18.7%,两组相比较,其差异无统计学意义(P〉0.05)。结论两性霉素B治疗白血病合并侵袭性真菌感染的疗效好,安全性高。
作者 尹薇 刘天宇
关键词 两性霉素B 疗效
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