摘要
睑板腺功能障碍（MGD）是临床常见的眼表疾病,以睑板腺终末导管阻塞和（或）睑板腺分泌物的质量和数量改变为特征.睑板腺脂质是由多种脂质组成的混合物,其构成了泪膜的脂质层,具有防止水分蒸发,维持泪膜稳定性的作用.MGD时,睑板腺脂质的成分将发生相应改变,是诊断MGD的重要指标.目前用于分析睑板腺脂质的主要方法包括色谱法和光谱法,但均不理想.由于MGD的病因尚不明确,故临床治疗方式以对症治疗为主.简便有效分析睑板腺脂质的质量和数量,将有助于临床诊断和治疗MGD.
Meibomian gland dysfunction （MGD） is a common ocular surface disease,characterized by terminal duct obstruction and （or） qualitative and quantitative changes in the glandular secretion.Meibomian lipids are a mixture consisting of various lipids,and they form the lipid layer of tear film and play important roles in preventing the evaporation and maintaining the stability of tear film.Patients with MGD may have different compositions of meibomian lipids,which could be an important indicator for diagnosis of MGD.The methods to analyze the composition of meibomian lipids mainly include chromatography and spectrum analysis.Because the pathogenic factors of MGD are still unclear,the main treatment is to relieve the symptoms.It can contribute to diagnose and treat MGD if we can find some convenient and effective methods to analyze the quality and quantity of meibomian lipids.
出处
《中华眼科杂志》
CAS
CSCD
北大核心
2015年第3期225-228,共4页
Chinese Journal of Ophthalmology
关键词
睑板腺
眼睑疾病
脂类
色谱法
光谱分析
Meibomian glands
Eyelid diseases
Lipids
Chromatography
Spectrum Analysis
