干性年龄相关性黄斑变性的研究及治疗进展

Progression of treatment and researches in dry age related macular degeneration

年龄相关性黄斑变性（AMD）是欧美国家引起中老年严重视力丧失最主要的原因.临床上可分为湿性黄斑变性或新生血管型黄斑变性和干性黄斑变性.目前有较多针对新生血管的有效治疗方法,而干性黄斑变性由于发病机制不明确、不会导致急性视力减退而不被重视、尚无恰当的临床治疗标准等多种原因,研究进展缓慢.现对国外干性黄斑变性的最新研究及治疗进展做出概述.

Age related macular degeneration （AMD） is the leading cause of blindness and visual disability among old patients in Europe and North America.AMD has been divided into two broad clinical categories depending on whether there is a presence of abnormal neovascularization：neovascular （exudative or wet） AMD and dry （or geographic atrophic）AMD.VEGF has been understood as a pathogenesis of wet AMD which allows us to get breakthroughs in treatment.While the progression of dry AMD treatment is very slow because the lack of pathogenesis,no acute loss of vision,and without appropriate standards for treatment.This review tries to introduce about the recent researches and progressions for dry AMD treatment.