标准前颞叶切除术联合常规病灶切除术治疗颅脑外伤继发顽固性癫痫的疗效

Effect of anterior temporal lobectomy combined with conventional lesionectomy on secondary intractable epilepsy with craniocerebral trauma

目的 观察颅脑外伤继发顽固性癫痫患者经常规病灶切除术后行标准前颞叶切除术治疗的临床效果.方法 选择2012年9月至2013年10月安阳市人民医院神经外科收治的80例颅脑外伤继发顽固性癫痫患者为研究对象,按照随机数字表法将其分为实验组与对照组,每组40例,两组患者均接受常规病灶切除术处理,实验组在此基础上行标准前颞叶切除术.术后进行至少半年的随访,对两组手术治疗效果进行评估.结果 与对照组相比,实验组治疗显效率以及总有效率更高,差异有统计学意义（P＜0.05）.结论 对于颅脑外伤继发顽固性癫痫患者而言,在常规病灶切除术基础上实施标准前颞叶切除术与单纯切除病灶相比效果更优,临床应予以推广和使用.

Objective To observe the effect of anterior temporal lobectomy combined with conventional lesionectomy on secondary intractable epilepsy with craniocerebral trauma.Methods Eighty patients with secondary intractable epilepsy with craniocerebral trauma who were admitted in the people＆#39; s hospital of Anyang from September 2012 to October 2013 were selected and randomly divided into experimental group and control group（40 cases in each group）.All patients were treated with conventional lesionectomy and the experimental group was treated with the standard anterior temporal lobectomy on this basis.The treatment effects of two groups were assessed for six months follow-up or longer.Results Compared with the control group,the experimental group had higher efficiency total efficiency and the differences were significant （P 〈 0.05）.Conclusions For patients of secondary intractable epilepsy with craniocerebral trauma,anterior temporal lobectomy combined with conventional lesionectomy will be more effective than conventional lesionectomy merely,therefore it is suggested to be promoted in clinic.