上海市32家样本医院2009-2012年抗肿瘤药应用分析

Analysis of the Utilization of Antitumor Drugs in Sample Hospitals from Shanghai during 2009-2012

目的:为临床合理使用抗肿瘤药提供参考。方法:调取上海市32家样本医院2009-2012年用药数据,运用Excel统计分析抗肿瘤药的销售金额、年同比增长率、市场份额以及科室分布等,并对样本医院及抗肿瘤药进行分类汇总、排序。结果:4年间抗肿瘤药用量增长迅速,2012年销售金额增长率达12.80%;从治疗大类分析,抗肿瘤中成药、抗代谢药和抗肿瘤植物药一直稳居销售金额前三位,总计占所有类别抗肿瘤药的50%以上,在恶性肿瘤的治疗中发挥着举足轻重的作用;从具体品种分析,多西他赛和卡培他滨的市场份额最大,销售金额始终排序前2位,而培美曲塞和替吉奥胶囊则是增速较快的2个品种。结论:近年来,抗肿瘤药物的应用呈现快速增长趋势,高选择性、高效低毒性的抗肿瘤药需求增大,抗肿瘤中成药应用广泛。

OBJECTIVE：To provide reference for the rational use of antitumor drugs in clinic. METHODS：The medication data of sample hospitals from Shanghai during 2009-2012 were collected and analyzed statistically by using Excel 2010 software in terms of consumption sum,year-on-year growth rate,market share of different drugs and hospitals,and prescription distribution among departments,etc. These sample hospitals and antitumor drugs were summarized and sorted. RESULTS：The amount of antitumor drug was soaring during the past 4 years,with a growth rate of 12.8% in 2012. By drug category Antitumor Chinese patent medicine and antimetabolites were the top two categories in the list of consumption sum,which accounted for 40% in the total and played important roles in malignant tumor therapy. By drug type,doceltaxel and capecitabine owned the largest market shares,accounting for 6.15% and 5.94%;while pemetrexed and Tegafur/gimeracil/oteracil potassium capsule showed the most significant increase. CONCLUSIONS：In recent years,the application of antitumor drugs in hospitals shows rapid growth. The demand of antitumor drugs with high selectivity,high potency and low side-effect is increasing,and antitumor Chinese patent medicine is widely used.