喹硫平治疗精神障碍研究进展

Progress Study on Quetiapine in the Treatment of Psychiatric Disorders

非典型抗精神病药喹硫平临床应用广泛,已批准用于治疗精神分裂症、心境障碍(急性躁狂发作、双相障碍、重度抑郁等)。临床试验发现喹硫平可治疗焦虑谱系障碍、痴呆的精神行为症状、失眠症、酒精依赖症等精神障碍。故本文主要综述喹硫平治疗焦虑谱系障碍、痴呆的精神行为症状、失眠症、酒精依赖症等精神障碍的随机对照试验结果,以期为精神科医生用药提供参考依据。

Atypical antipsychotic drug quetiapine was approved for the treatment of schizophrenia, acute mania, acute bipolar disorder and major depression. Some clinical trials provided evidences for the efficacy of quetiapine in the anxiety spectrum disorders, behavioral and psychological symptoms of dementia, insomnia and alcoholism. This paper reviewed mainly the results of quetiapine in the treatment for anxiety spectrum disorders, behavioral and psychological symptoms of dementia, insomnia, alcoholism in random control trials.