二维和三维超声测量单卵泡直径的一致性研究

Research on the consistency of two-dimensional and three-dimensional ultrasonography in diameter measurement of single follicle

目的三维超声自动容积测量逐步在临床应用中表现出众多优点,并成为超声医学的一个重要发展方向。文中评估二维和三维超声对于单卵泡直径测量的一致性。方法对438枚单卵泡发育的卵泡分别进行二维超声和三维超声方法的测量,记录所得的二维直径、三维平均直径、三维虚拟球径,通过Bland-Altman Plot法对二维直径和三维平均直径、二维直径和三维虚拟球径分别进行一致性评估。结果在二维直径和三维平均直径2种测量方式对于单卵泡直径的测量的一致性分析中,差值的均数d=-1.06 mm,95%Lo A为(-4.82,2.70)mm,95%Lo A的95%CI为(-5.21,3.08),临床可接受一致性区间d±l0为(-3.56,1.44)mm,(-5.21,3.08)mm(-3.56,1.44)mm,一致性不佳;在二维直径和三维虚拟球径2种测量方式对于单卵泡直径的测量的一致性分析中,差值的均数d=-0.07 mm,95%Lo A为(-3.11,2.98)mm,95%Lo A的95%CI为(-3.43,3.29)mm,临床可接受一致性区间d±l0为(-2.57,2.43)mm,(-3.43,3.29)mm(-2.57,2.43)mm,一致性不佳。结论三维和二维超声测量方法对于单卵泡直径测量结果并不一致,但考虑到其在结果获得的客观性与精确性方面较二维超声仍然具有优势,可以为辅助生育技术提供更为精确的帮助。

Objective Three-dimensional（3D） automated ultrasonic volume measurement is becoming favorable in clinical application and turns to be an important direction .The article was to evaluate the consistency of two-dimensional （2D） and three-di-mensional ultrasonography in the diameter measurement of single follicle . Methods 438 single folliculars were respectively meas-ured by the same sonographer in 2D and 3D ultrasonic measurement.2D diameter, 3D mean diameter and 3D virtual ball diameter of every single follicle were recorded , and Bland-Altman method were used to evaluate the consistency of the results by these two meth-ods. Results In the consistency analysis on the diameter measurement of single follicle by 2D and 3D mean diameter measurment methods, d equaled -1.06 mm, and 95% LoA range covered the range of -4.82 mm to 2.70 mm.95% CI of 95% LoA range,-5.21 mm to 3.08 mm, was beyond the settings of clinical acceptable error limit range , -3.56 mm to 1.44 mm, showing poor consis-tency.Likewise, in the research of the consistency in the measurement of 2D diameter and 3D virtual ball diameter in the diameter measurement of single follicle , d equaled -0.07 mm , and 95%LoA range covered the range of -3.11 mm to 2.98 mm.95%CI of 95%LoA range, -3.43 mm to 3.29 mm, was beyond the settings of clinical acceptable error limit range , -2.57 mm to 2.43 mm, showing poor consistency . Conclusion 2D and 3D ultrasound measurements in the diameter measurement of single follicle are not consistent.However, considering the objectivity and accuracy of the results , 3D ultrasonography still has an advantage over 2D ultra-sonography , which can provide more acurate aid for assisted reproductive technology .