阿托伐他汀对高血压患者血压与炎症因子的临床影响效果观察

The clinical observation of the effect of atorvastatin on blood pressure and inflammatory factors of hypertensive patients

目的：观察阿托伐他汀对高血压患者血压与炎症因子的影响，以便为高血压的临床治疗提供参考依据。方法：本次研究选取的病例资料均为2010年12月～2013年12月我院治疗的高血压患者。全部入选对象共计48例，全部患者均给予阿托伐他汀进行治疗。观察和比较患者实施治疗前后的观察指标为入选患者实施治疗前后的收缩压、舒张压、超敏C反应蛋白、白介素-1、白介素-6水平。结果：①治疗后，患者收缩压和舒张压水平均显著降低；②治疗后，患者的各项炎症因子水平均显著降低，差异具有统计学意义。结论：在临床针对高血压实施治疗的实践过程中，阿托伐他汀可显著改善患者血压降低炎症因子水平。

Objective：To further investigate the actual effect of atorvastatin on blood pressure and inflammatory factors of hypertensive patients, so as to provide reference for clinical treatment and research of hypertension. Methods：48 cases of hypertensive patients of the study were selected in our hospital from 2010 December to 2013 December. All patients were given atorvastatin treatment. Systolic pressure, diastolic pressure, high sensitive C reactive protein, interleukin -1, interleukin -6 of the patients before and after treatment were observed and compared.Results：①After treatment, the systolic and diastolic blood pressure of the patients were markedly reduced;②After treatment, the levels of inflammatory cytokines of the patients were significantly decreased, the data were statistically significant.Conclusion： In clinical practice for patients with hypertension treatment in clinical practice, atorvastatin can significantly improve patients＇ blood pressure and decrease the level of inflammatory factors.