美托洛尔联合胺碘酮治疗房颤临床效果

Clinical Efficacy Experience of Metoprolol Combined With Amiodarone in Treatment of Atrial Fibrillation

目的：进一步探究美托洛尔联合胺碘酮治疗房颤临床效果。方法收集2012年1月～2012年12月我院收治的88例房颤患者临床资料进行详细探究，将上述患者随机分为两组，44例对照组患者接受胺碘酮治疗，44例研究组患者在对照组治疗基础上，加用美托洛尔治疗。结果研究组患者临床治疗有效率高于对照组，P〈0.05，具有差异统计学意义。治疗后研究组患者心室率评分（119.6±15.6）优于对照组（139.8±12.6），P〈0.05，具有差异统计学意义。两组患者均未出现严重不良症状。结论美托洛尔联合胺碘酮治疗房颤临床效果显著。

Objective To explore treatment efficacy of metoprolol combined with amiodarone in treatment of atrial fibrillation. Methods Reviewed clinical treatment data selected from 88 atrial fibrillation patients who were treated in hospital from January 2012 to December 2012 and separated them into two groups at random. 44 patients in control group were given amiodarone treatment only; while 44 patients in study group were given metoprolol combined with amiodarone treatment. Results Treatment efficacy in study group was higher than treatment efficacy in control group,there was a treatment differential between two groups,and such a differential had statistic value（P〈0.05）. Besides,patients’ventricular rate score in study group（119.6±15.6）was significantly higher than that in control group（139.8±12.6）, there was a treatment differential between two groups,and such a differential had statistic value（P〈0.05）. But there was no serious side effect to be seen in two groups. Conclusion Metoprolol combined with amiodarone is of efficacy in treatment of atrial fibrillation,which is quite worthwhile to be promoted.