心理干预前后体外受精-胚胎移植患者的心理状态调查及其影响

The Psychological State Investigation of the Patients with Infertility Receiving in Vitro Fertilization-embry Transfer and the Impact of the Psychological Intervention

目的调查不孕症接受体外受精-胚胎移植(in vitro fertilization-embry transfer,IVF-ET)女性患者的心理状态并探讨心理干预的影响。方法选取我院诊治的150例接受IVF-ET的女性患者为观察组(75例心理干预亚组,另75例为非心理干预亚组);另选150例在我院接受体检的正常育龄期已婚妇女为对照组。对所有研究对象进行一般情况、心理情况和婚姻情况调查,填写焦虑自评量表(SAS)和抑郁自评量表(SDS)评估其心理状态,并在IVF-ET结束后再次进行心理调查。比较心理干预组与非心理干预组两组间及心理干预组心理治疗前后心理情况评分的变化。结果观察组SAS评分(60.54±10.23)及SDS评分(63.43±8.83)均显著高于对照组,差异有统计学意义(P<0.01);接受IVF-ET治疗的患者中,81.3%(122例)处于焦虑状态,90.0%(135例)处于抑郁状态。接受心理干预的75例患者中,经心理干预后,焦虑及抑郁评分均显著下降,差异有统计学意义(P<0.01)。与未接受心理干预的患者相比,接受心理干预的患者焦虑及抑郁评分均显著下降,差异有统计学意义(P<0.01)。结论不孕症患者易产生焦虑、抑郁等不良心理压力,通过有效的心理干预可改善患者的心理状态。

Objective To investigate psychological state of the infertile female patients who receive in vitro fertiliza-tion-embry transfer（ IVF-ET） and to explore the impact of the psychological intervention. Methods One hundred and fifty infertile female patients who would receive IVF-ET were enrolled as the studied subjects（ divided into psychologicalintervention group and non-psychological intervention group evenly） while 150 healthy married females were enrolled as the control. The general informa-tion,psychological state information[ Self-rating anxiety scale（ SAS） and Self-rating depression scale（ SDS） ] ,marriage and fertility information was collected from every subject. The psychological status of the two subgroups were compared. Results The SAS and the SDS of the IVF-ET group was （ 60. 54 ± 10. 23 ） and （ 63. 43 ± 8. 83 ） , which was significantly higher than those of the healthy control group（P 〈0. 01）;in the IVF-ET group,81. 3%（122 cases） of the patients present as the anxiety state while 90. 0%（135 cases）patients present as the depression state. In the psychological intervention subgroup,the SAS and SDS both was decreased after the psychological therapy（P〈0. 01）. Compared with the non-psychological intervention subgroup,the patients in the psychological intervention group after the psychological therapy,the SAS and SDS both was decreased（P〈0. 01）. Conclusion Infertile patients produce the noxious psychological problems such as anxiety and depression due to the pressure from the society, family and the therapy. Effective psychological intervention could improve the psychological state of the patiets and might boost the successful fertility rate.