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阿司匹林在脾切除术后的临床应用

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摘要 目的探讨脾切除后外周血指标的变化规律与脾切除后继发脑梗死并发症的关系,以及应用阿司匹林后对脾切除患者外周血指标的影响,观察阿司匹林预防脾切除后继发脑梗死的临床疗效。方法 118例接受脾切除术患者随机分为两组,治疗组42例术后服用阿司匹林肠溶片100 mg/d,对照组76例未服用阿司匹林,分析术前术后外周血指标的变化与并发脑梗死的关系。结果治疗组与对照组血小板数、血小板平均体积、血小板聚积率术后3、6个月比较,差异有统计学意义(P<0.05),治疗组未发生脑梗死病例,对照组1、3、6个月内并发脑梗死的比例为2.6%、14.5%、3.9%;组间数据对比差异有统计学意义(P<0.05),且治疗组未发生严重药物不良反应。结论脾切除术后应用阿司匹林可显著改善患者外周血指标,能有效预防术后脑梗死并发症的发生。
出处 《中国现代药物应用》 2015年第9期128-130,共3页 Chinese Journal of Modern Drug Application
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