结节纵横比>1对不同大小甲状腺乳头状癌超声诊断价值的研究

目的探讨结节纵横比〉1（A/T〉1）对不同大小甲状腺乳头状癌（papilary thyroid carcinoma,PTC）的诊断价值。方法回顾性收集并整理了行甲状腺超声检查并经病理结果证实的124例患者共207个甲状腺结节的纵横比,按结节的大小分为3组：A组PTC病灶最大径≤0.5 cm、B组PTC病灶最大径为0.5~1.0 cm（〉0.5 cm且≤1.0 cm）,C组PTC病灶最大径为〉1.0 cm。比较结节纵横比诊断不同大小PTC的敏感性、特异性、阳性预测值、诊断比值比及阳性似然比。结果对于不同大小的PTC,A/T〉1在A组患者中的敏感度和特异度均最高,在C组患者中最低。结论对于最大直径≤0.5 cm的PTC,A/T〉1是有效的超声诊断指标,但对于最大直径〉1.0 cm的PTC,A/T≥1不适宜做为主要的诊断标准。

ObjectiveTo evaluate A/T〉1 for papillary thyroid carcinoma （PTC） according to nodule size.Methods We retrospectively examined 207 thyroid nodulesfrom 124 patients. Nodules were divided into 3 groups by size： small （≤0.5 cm, group A）, medium （0.5–1cm, group B）, and large （〉1 cm, group C）. Compare the sensitivit、speciifcity、positive predict value,diagnostic odd ratio and diagnostic accuracy of A/T〉1.Results The sensitivit and speciifcity of A/T〉1 with PTC is the highest in the group A,and the lowest in the group C.Conclusion A/T〉1 showed superior performance for PTC diagnosis in nodulese≤0.5cm,but a low sensitivity and diagnostic accuracy for PTC diagnosis in nodules 〉1cm.