血液细胞成分与男性冠状动脉慢血流的关系

Correlation between blood cell parameters and slow coronary flow in male patients

目的：探讨血液细胞成分与男性冠状动脉慢血流（ SCF）的关系。方法2011年8月至2012年8月经造影证实冠状动脉狭窄＜40％的男性患者199例，根据校正的TIMI血流计帧法分为SCF组151例，正常对照组48例，比较2组临床变量。结果2组高血压病、2型糖尿病、吸烟史和冠脉轻度狭窄比例差异无统计学意义（P ＞0．05）。 SCF组年龄较低，而高脂血症比例高于正常对照组（ P ＜0．05）。血液细胞成分比较发现SCF组白细胞计数[6．70（5．62，7．94），6．12（5．38，6．65）]、血红蛋白[150（142，157），145（137，151）]和红细胞压积[43．2（40．74，5．0），42．2（40．4，44．2）]高于正常对照组（ P ＜0．05），多因素分析提示高脂血症（ P ＝0．014，OR 2．385，95％CI 1．197～4．753）和血红蛋白（ P ＝0．030，OR 1．034，95％CI 1．003～1．066）是SCF的独立影响因素。结论高脂血症和血红蛋白是男性冠状动脉SCF的临床影响因素。

Objective To analyze the correlation between blood cell parameters and slow coronary flow （ SCF ） in male patients .Methods One hundred and ninety-nine male patients with coronary stenosis identified by coronary arteriongraphy （ stenosis 0.05）.The patient＇s age in SCF group was lower than that in control group ,however,the proportion of hyperlipidemia in SCF group was higher than that of control group （ P 〈0.05）.There were significant differences in white blood cell count [6.70（5.62,7.94）vs 6.12（5.38, 6.65）],hemoglobin[150（142,157）vs 145（137,151）],hematocrit[43.2（40.7,45.0）vs 42.2（40.4,44.2）] between two groups （ P 〈0.05）.Multifactor analyses showed that hyperlipidemia （OR 2.385,95% CI 1.197~4.753, P 〈0.05）and hemoglobin（OR 1.034,95% CI 1.003 ~1.066, P 〈0.05） were independent influencing factors for SCF .Conclusion Hyperlipidemiaand hemoglobin are risk factors of SCF ,which suggests that the increase of these parameters may contribute to the pathogenesis of SCF in male patients .