匹多莫德辅治婴幼儿毛细支气管炎疗效观察

Effect observation of pidotimod in the adjuvant treatment of capillary bronchitis in children

目的探讨匹多莫德辅助治疗儿童毛细支气管炎的临床疗效。方法收集2009年2月-2010年4月儿科门诊及病房符合毛细支气管炎诊断的患儿50例,随机分为治疗组与对照组各25例。对照组采用布地奈德,沙丁胺醇交替雾化,采用抗病毒药物,根据感染情况添加抗生素,并给予激素静脉滴注。治疗组在对照组基础上加用匹多莫德片。比较2组患儿治疗后的临床疗效。结果对照组总有效率为72.0%,治疗组总有效率为84.0%,治疗组患儿治疗后疗程较对照组缩短,差异有统计学意义(P<0.05)。治疗期间未见明显不良反应,患儿依从性100.0%。结论匹多莫德用于儿童反复呼吸道感染临床急性期治疗、缓解期预防均有明显疗效,且无明显不良反应,为口服剂型,使用方便,减轻了患儿的痛苦,并减少了在院时间,值得推广。

Objective To study the clinical effect of pidotimod in the adjuvant treatment of capillary bronchitis in children.Methods 50 cases of children with capillary bronchitis were randomly divided into treatment group and control group,each of 25 cases.The control group received budesonide and salbutamol alternative atomization ,antiviral therapy,antibi-otics treatment according to the infection degree and hormone infusion .Based on the control group , the treatment group was added with pidotimod for treatment .The clinical efficacy of 2 groups was compared .Results The total effective rate of treat-ment group was 84.0%,while the control group was 72.0%,and the course of treatment in the treatment significantly short-ened compared with the control group,the differences were statistically significant （P〈0.05）.During the treatment period, there was no obvious adverse reaction .The compliance of children was 100%.Conclusion The curative effect of pidotimod is obvious in the clinical treatment of acute period of children with recurrent respiratory tract infection and the prevention of re -mission stage,with no obvious adverse reaction ,for oral dosage,convenient to use,which reduces the pain of the patients and Reduces the length of stay .It is worthy of popularization .