百蕊颗粒辅助治疗小儿急性上呼吸道感染临床观察

Clinical Observation of Adjuvant Therapy with Bairui Particles for Children with Acute Upper Respiratory Tract Infection

目的:观察百蕊颗粒辅助治疗小儿急性上呼吸道感染的临床疗效。方法:180例急性上呼吸道感染患儿随机分为对照组和观察组各90例。在常规治疗基础上,对照组予利巴韦林10 mg·kg-1·d-1,qd,观察组在对照组基础上再加用百蕊颗粒。比较两组临床疗效,主要临床症状体征改善时间、住院时间及药品不良反应。结果:除啰音消失时间外,观察组临床症状体征改善时间及住院时间均较对照组明显缩短(P<0.05);观察组显效率、总有效率均明显高于对照组(P<0.05)。两组药品不良反应发生率比较,差异无统计学意义(P>0.05)。结论:百蕊颗粒辅助治疗小儿急性上呼吸道感染能显著改善患儿症状体征,疗效显著,值得临床推广。

Objective： To observe the clinical efficacy of Bairui particles in the treatment of children with acute upper respiratory tract infection. Methods： Totally 180 children with acute upper respiratory tract infection were randomly divided into the control group and the study group. The control group was treated with conventional therapy,such as ribavirin（ 10 mg·kg- 1·d^-1,qd） and so on,and the study group received Bairui particles additionally. The improvement time of clinical symptoms,hospitalization time,clinical efficiency and adverse reactions were compared. Results： Except the rale disappearance time,the improvement time of clinical symptoms and hospitalization time in the study group were shorter than those in the control group（ P〈0. 05）. The obvious effective rate and total effective rate in the study group were also higher than those in the control group（ P〈0. 05）. There was no significant difference in adverse drug reactions between the two groups（ P〉0. 05）. Conclusion： Bairui particles are effective for the children with acute upper respiratory tract infection,which are worthy of wide clinical use.