医院如何建设富有生命力的生物样本资源库

Construction of a Dynamic Biobank of Hospital

近十年来,国内医院生物样本资源库的建设有了长足的发展和进步。同时,各种困扰医院领导和广大生物样本资源库建设者的问题日益显现出来,并成为制约医院生物样本资源库进一步可持续健康发展的关键问题。全文总结作者十年来从事医院生物样本库建设以及第三方生物样本资源库中心建设的经验,针对目前医院生物样本资源库建设全过程可能存在的突出问题,从医院生物样本资源库的顶层设计与构建、生物样本资源质量管理体系建设、以及如何建立和完善生物样本资源库可持续健康发展的自身造血机制等宏观角度进行了较为系统地阐述。在一定程度上为医院领导和生物样本资源库建设者理清了思路和方向,破解了当前困扰医院生物样本资源库可持续健康发展的瓶颈问题,给医院生物样本资源库建设工作提供了有益的指导。

Over the past decade,great progression in the construction of hospital biobank has been made in China. Meanwhile,hospital leaders and biobank constructors face new challenges and problems,which become the key issues restricting the further sustainable and healthy development of the hospital biobank. This paper systematically summarized a decade of author ＇s experience in the construction of hospital and third-party biobanks. From a more macro perspective,it elaborated current common problems in hospital biobank construction,including top-level design and construction,quality management system,self-support system and sustainable development. To a certain extent,it sorted out ideas for the hospital leaders and biobank builders,addressed current hospitals biobank sustainable and healthy development bottlenecks,and provided useful guidance for hospital biobank construction.