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N-甲基-D-天冬氨酸受体基因多态性与常见精神障碍疾病的研究进展 被引量：1

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摘要 近20年来,精神分裂症、双相情感障碍、抑郁症等精神疾病的病理学研究有了长足进步.DSM-5中将生物学特征与临床症状相结合对精神疾病进行分类和诊断,由于具体的发病机制不清,精神疾病仍被归因于多因素共同作用.遗传学研究显示大部分精神疾病均为复杂的多基因遗传病,遗传因素比环境因素更重要.张治坤等[1]发现,精神分裂症高发家系患者及其家属的认知缺陷较单发家系更明显.目前我国因精神疾病所造成的总社会负担达20％,已超过心脑血管疾病、呼吸系统疾病及恶性肿瘤等排名居首位.
作者 廖潇潇 钟舒明 刘滔 何婷婷 谌建 贾艳滨
机构地区 暨南大学第一临床医学院 暨南大学附属第一医院精神心理科 暨南大学管理学院
出处 《中华精神科杂志》 CAS CSCD 北大核心 2015年第2期121-125,共5页 Chinese Journal of Psychiatry
基金 广东省教育厅科技创新项目（2013KJCX0025） 教育部人文社会科学研究规划基金项目（13YJAl90008）
关键词 N-甲基-D-天冬氨酸 精神疾病 精神障碍 受体基因多态性 精神分裂症 双相情感障碍 多基因遗传病 心脑血管疾病
分类号 R749 [医药卫生—神经病学与精神病学]
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参考文献33

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二级参考文献75

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中华精神科杂志
2015年 第2期

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