曼月乐环治疗近绝经期子宫肌瘤患者的疗效观察

Curative effect observation of Mirena on nearly menopausal hysteromyoma patients

目的：探讨对近绝经期子宫肌瘤患者放置曼月乐环的疗效观察。方法选用我院42-48岁子宫肌瘤患者60例，治疗前均行宫腔镜探查术排除子宫内膜疾病，排除宫腔形态失常，排除黏膜子宫肌瘤可能。在充分知情告知患者，签署同意书、排除曼月乐环使用禁忌症后，于月经干净3天对患者实施放置曼月乐环。放置曼月乐环后3月、6月、12月分别复查B超测量子宫肌瘤直径变化。通过监测放置曼月乐环后3月、6月、12月血红蛋白及B超测量子宫内膜厚度，观察放置曼月乐环对月经过多患者的疗效。结果放置曼月乐环后3月、6月及1年子宫肌瘤直径明显缩小，有统计学差异（P＜0．05）。有月经过多症状患者放置曼月乐环后3月及6月，月经量明显减少，血红蛋白明显回升，子宫内膜厚度明显变薄，有统计学差异（P＜0．05）。结论近绝经期子宫肌瘤患者尤其伴随月经过多患者放置曼月乐环疗效好，可推荐使用。

Objective To discuss treatment on nearly menopausal hysteromyoma patients placed Mirena. Methods Chose from 42 to 48 years old, 60 patients with uterine fibroids, before treatment of hysteroscopy in surgical exploration to rule out endometrial disease, eliminate disorder caused by intrauterine form, uterine fibroids may exclude mucosa.In fully informed informed patient, sign the consent form, rule out the use of contraindications, Placed Mirena after menstruation clean 3 days for patients, Placed Mirena respectively in March, June, 12 month review ultrasound measurement uterine fibroids diameter changes.By monitoring Mirena placed Raman months in March, June, December hemoglobin and ultrasound measurement, endometrial thickness Mirena observation place, month of menorrhagia patients curative effect.Results Placed Mirena after 3 months, 6 months and 1 year uterine fibroids significantly smaller diameter, statistically significant （P〈0.05）.Patients with symptoms of menorrhagia placed 3 month and 6 month after Mirena, menstrual quantity decreased significantly, hemoglobin rebounded, endometrial thickness thinning, statistically significant （ P 〈0.05 ）. Conclusions Nearly menopausal hysteromyoma patients especially with menorrhagia patients placed Mirena curative effect is good, can be recommended.