奥曲肽不同给药方式治疗胰腺炎疗效对比分析

Comparative Analysis of Curative Effect of Octreotide in Treatment of Acute Pancreatitis of Different Ways of Administration

目的对奥曲肽不同给药方法治疗胰腺炎的疗效进行对比分析。方法选取我院于2013年11月-2014年9月收治的38例胰腺炎患者随机分成对照组和治疗组,对照组患者给予奥曲肽静滴1小时滴完,治疗组患者给予奥曲肽微量注射泵持续注射给药持续12小时,对两组患者的临床疗效进行对比。结果治疗组患者的淀粉酶恢复时间、腹痛消失时间、住院天数、不良反应发生率以及治疗总有效率与对照组比较,差异有统计学意义（P〈0.05）。结论奥曲肽微量注射泵持续注射给药方式治疗胰腺炎效果显著,不仅能够大大降低不良反应发生率还能缩短患者的住院时间,对促进患者快速康复以及提高患者的生活质量有着重要意义。

Objective Comparative study of different ways of octreotide administering in treatment of pancreatitis is to be investigated.Methods Choose 38 patients with pancreatitis who are treated in hospital from November 2013 to September 2014 and separate them into control group and study group at random. Patients in control group are given intravenous infusion treatment of octreotide drop lasting for an hour, while patients in study group are given octreotide injection treatment by syringe pump lasting for continuous 12 hours, and then compare treatment efficacy of these two groups.Results The comparative result shows that patients’ amylase recovery time, abdominal pain disappeared time, hospitalization days, and side-effect incidence and treatment efifcacy in study group are quite differential from those in control group; and such a differential has statistic value （P〈0.05）.Conclusion Treating pancreatitis patients with octreotide injection treatment by syringe pump for continuous hours is conducive to significantly reducing side-effect incidence and shortening patients’ hospitalization days, which is of signiifcance to improve patients’ recovery and bettering their quality of life.