喀什地区维吾尔族溃疡性结肠炎临床特征分析

Clinical Features of Ulcerative Colitis in Kashi Uygur Nationality

背景:近年来溃疡性结肠炎(UC)的发病率逐年升高,且发病特征具有明显的地域和种族差异。目的:探讨喀什地区维吾尔族(维族)UC的临床特征。方法:纳入2003年2月-2012年2月新疆喀什地区第二人民医院确诊的维族UC患者,对入组患者的一般情况、UC临床类型、疾病严重程度、病变部位、并发症以及治疗情况进行回顾性分析。结果:共126例患者纳入研究。男女比例为1.03∶1(64/62),青年为高发年龄段(48.4%);临床类型以慢性复发型多见(50.0%);疾病严重程度以中重度多见(83.3%);病变部位以左半结肠为多见(45.2%);并发症发生率低(4.8%);治疗以内科药物为主。结论:喀什地区维族UC患者男女性别无明显差异,以青年高发,慢性复发型多见,疾病严重程度以中重度多见,病变部位以左半结肠多见,并发症发生率低,治疗以内科药物为主。

Background：The incidence of ulcerative colitis（ UC）has increased obviously in recent years and is different among different areas and nationalities. Aims：To investigate the clinical features of UC in Kashi Uygur nationality. Methods：A retrospective analysis was conducted based on general condition, clinical type, disease severity, sites of lesion, complications and treatment on patients with UC who were enrolled from February 2003 to February 2012 at the Second Hospital of Kashi Area. Results：One hundred and twenty-six eligible subjects were enrolled in this study. The ratio of male to female was 1. 03： 1（64/62）. UC occurred commonly in youth（48. 4%）. Chronic relapsing UC was the common clinical type（50. 0%）. Most patients were with moderate or severe disease（83. 3%）. Lesions of UC were commonly located in left hemicolon（ 45. 2%）. Incidence of complication was low（ 4. 8%）. Medical treatment was the main treatment. Conclusions：In Kashi Uygur nationality,the incidence of UC is not significantly different between male and female. UC commonly occurs in youth,chronic relapsing UC is the common clinical type,most patients are with moderate or severe disease,lesions of UC are commonly located in left hemicolon,the incidence of complication is low and medical treatment is the main treatment.