结肠腺瘤发生的危险因素的临床分析

Clinical analysis on risk factors of colonic adenoma

目的探讨结肠腺瘤发生的危险因素。方法回顾分析郑州市第一人民医院2010年1月-2013年12月收治的102例结肠腺瘤患者,并随机选取150例正常人作为对照组。记录相关高危因素,应用SPSS 15.0统计软件进行数据分析,结肠腺瘤相关因素分析采用多因素Logistic回归分析。结果多因素Logistic回归分析示年龄、癌症家族史、高脂血症、喜食红肉为独立危险因素,喜食果蔬为保护性因素。结论对于年龄≥60岁的男性,具有癌症家族史、高脂血症、喜食红肉的人群,改善生活方式、多食新鲜的水果蔬菜、定期检查电子结肠镜,可早期发现结肠腺瘤,减少结肠癌的发生。

Objective To investigate the risk factors that may be associated with colonic adenoma. Methods Pa- tients who underwent complete colonoscopy at the First People＇ s Hospital of Zhengzhou from Jan. 2010 to Dec. 2013 were enrolled into this study, 102 subjects were found colonic adenoma （colonic adenoma group） and the other 150 were found normal （control group）. The related risk factors were recorded, the data were statistically analyzed by SPSS 15. O, Logistic regression was applied to evaluate the independent risk factors for colonic adenoma. Results Multivari- ate Logistic regression analysis showed that age, family history of cancer, hyperlipidemia, and high proportion of red meat intake were independent risk factors for colonic adenoma, while high proportion of fresh fruitsand vegetables intake was protective factor. Conclusion For men whose age≥60 with a family history of cancer, hyperlipidemia, high pro- portion of red meat intake, improving the way of life, eating fresh fruits and vegetables, and regularly checking the elec- tronic colonoscopy could discover colon adenoma early and reduce the occurrence of colon cancer.