功能性消化不良不同亚型临床特征研究

Clinical characteristics of functional dyspepsia in different subgroups

目的探讨功能性消化不良不同亚型患者精神心理因素、睡眠质量、生活质量方面的差异性。方法功能性消化不良患者120例,分为上腹痛综合征(epigastric pain syndrome,EPS)、餐后不适综合征(postprandial distress syndrome,PDS)和重叠型三组,均进行Zung氏焦虑自评量表、Zung氏抑郁自评量表、SF-36生活质量调查量表和匹茨堡睡眠质量指数量表评定。结果 (1)三组间在焦虑患病率、抑郁患病率、睡眠障碍患病率上比较差异均有统计学意义(P<0.05);(2)三组患者在生理功能、情感职能、活力、精神健康、社会功能、躯体疼痛、总体健康方面比较差异有统计学意义(P<0.05),其中重叠型组评分最高;在生理职能方面三组之间差异无统计学意义(P>0.05)。结论功能性消化不良不同亚型患者焦虑、抑郁患病率,睡眠障碍率不同,生活质量有一定差异,针对功能性消化不良不同亚型患者的临床特征,有助于制定有效的治疗方案,对于提高功能性消化不良患者的生活质量有重要意义。

Objective To investigate the differences of psychological factors, sleep quality and the life quality of functional dyspepsia in different subgroups. Methods 120 patients with functional dyspepsia were divided into epigas- tric pain syndrome, postprandial distress syndrome and overlapping, then zung＇ s self rating anxiety scale, zung＇ s self rating depression scale, SF-36 quality of life questionnaire and pittsburgh sleep quality index were used in the three groups . Results （ 1 ） The prevalence of anxiety, prevalence of depression, prevalence of sleep disorder in three groups had statistical significance difference （P 〈 0. 05 ）. （2）There were statistically significant differences of physiological function, emotional function, mental health, vitality, social function, body pain and general health among the three sub- groups （ P 〈 0.05 ） , the overlapping had the highest score ; there was no statistically significant difference of physiological functional among the three groups （P 〉 0.05）. Conclusion The rates of patients who had anxiety symptom, depressive symptom and sleep disorder are different in functional dyspepsia in different subgroups; the quality of life is different. According to the clinical characteristics of functional dyspepsia in different subgroups, it is helpful to formulate effective therapeutic plan and it also has important significance in improving the life quality of functional dyspepsia patients.