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抗病毒药物治疗急性视网膜坏死综合征进展 被引量:7

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摘要 急性视网膜坏死综合征(acute retinal necrosis syndrome,ARNS)主要是由疱疹族病毒引起的一种严重致盲性眼病,早期有效及时地抗病毒药物治疗是减少失明的重要手段之一。目前的研究认为静脉使用阿昔洛韦、更昔洛韦可以有效控制病情发展,减少对侧眼的发病率。新型的口服抗病毒药物伐昔洛韦、缬更昔洛韦、泛昔洛韦等生物利用度更高,成为治疗ARNS的另一选择。玻璃体腔内注射膦甲酸钠、更昔洛韦可以在眼内形成较高药物浓度并直接作用于病灶,有利于控制病情发展。这些新的抗病毒药物以及不同的用药方式使ARNS有了良好预后。
出处 《中国实用眼科杂志》 2015年第3期217-219,共3页 Chinese Journal of Practical Ophthalmology
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  • 1Tran TH, Rozenberg F, Cassoux N, et al. Polymerase chain reac- tion analysis of aqueous hmour samples in necrotising retinitis [J]. Br Ophthalmol,2003,87:79-83.
  • 2Kramer S, Brummer C,Zierhut M,et al. Epstein-Barr virus asso- ciated acute retinal necrosis IJ]. Br J Ophmalmol,2001,85 (1) : 114.
  • 3Holland GN. Standard diagnostic criteria for the acute retinal necrosis syndrome.Executive Committee of the American Uve- itis Society[J]. Am J Ophthalmol,1994,117:663-667.
  • 4Ganatra JB, Chandler D, Santos C, et al.Viral causes of t! acute retinal necrosis syndrome[J]. Am J Op|athalmol, 200( 129: 166-172.
  • 5Balfour HH. Antivira! drugs LJJ. New Eng J Med, 1999, 340: 1255-1268.
  • 6Blumenkranz MS,Culbertson WW,Clarkson JG, et al. Treatment of the acute retinal necrosis syndrome with intravenous acyclovir [J]. Ophthalmology, 1986,93 : 296-300.
  • 7Tibbets MD,Shah CP,Young LH,et al. Treatment of acute reti- nal necrosis[J]. Ophthalmology. 2010,117: 818-824.
  • 8Jeon S,,Kakizaki H,Won-Ki L, et al. Effect of prolonged oral acyclovir reatment in acute retinal neerosis[J~. Ocul Immunol Inflarnm, 2012,20(4) : 288-292.
  • 9Morse LS, Mizoguchi M. Diagnosis and management of viral reti- nitis in the acute retinal necrosis syndrome[J~. Semin Ophthal- mol, 1995,10:28-41.
  • 10Crumpacker CS, Schnipper LE, Zaia JA, et al. Growth inhibition by acycloguanosine of herpes viruses isolated from human infec- tions [ J ]. Antimicrob Agents Chemother. 1979,15 : 642-645.

二级参考文献21

  • 1Urayama A, Yamada N, Sasaki J, et al. Unilateral acute uveitis with retinalperiarteritis and detachment. Jpn J Clin Ophthalmol, 1971,25:607-619.
  • 2Morse LS, Mizoguchi M. Diagnosis and management of viral retinitis in the acute retinal necrosis syndrome. Semin Ophthalmology, 1995,10:28-41.
  • 3Clarkson JG, Blumenkranz M, Culbertson WW, et al. Retinal detachment following the acute retinal necrosis syndrome. Ophthalmology, 1984,91 : 1665-1667.
  • 4Hou CH, Chen SN, Ho JD, et al. Surgical treatment of retinal detachment following acute retinal necrosis syndrome: surgical results in four patients. Chang Gung Med J, 2003,26:835-842.
  • 5Blumenkranz M, Culbertson WW, Clarkson JG, et al. Treatment of the acute retinal necrosis syndrome with intravenous acyclovir. Ophthalmology, 1986,93 : 296-300.
  • 6Henry K, Cantrill H, Fletcher C, et al. Use of intravitreal ganciclovir ( dihydroxy propoxymethyl guanine) for cytomegalovirus retinitis in a patient with AIDS. Am J Ophthalmol, 1987,103:17- 23.
  • 7Luu KKM, Scott IU, Chaudhry NA, et al. Intravitreal antiviral injections as adjunctive therapy in the management of immunocompetent patients with nectrotizing herpetic retinopathy. Am J Ophthalmol,2000,129 :811-813.
  • 8Chau TH, Cassoux N, Bodaghi B, et al. Successful treatment with combination of systemic antiviral drugs and intravitreal ganciclovir injections in the management of severe necrotizing herpetic retinitis. Ocul Immunol Inilamm ,2003,11 : 141-144.
  • 9Geroski DH, Edelhauser HF. Transscleral drug delivery for posterior segment disease. Adv Drug Deliv Rev,2001,52:37-48.
  • 10Cunha-Vaz JG. The blood-ocular barriers: past, present and future. Doc Ophthalmol, 1997,93 : 149-157.

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同被引文献49

  • 1郭源源,朱丹,陶勇.急性视网膜坏死的研究进展[J].中华眼科医学杂志(电子版),2013,3(4):236-239. 被引量:8
  • 2韩曙霞,郑曰忠.病毒性角膜葡萄膜炎的诊断和治疗[J].临床眼科杂志,2007,15(2):181-183. 被引量:5
  • 3赵举峰,杨慧兰.潜伏相关转录体对单纯疱疹病毒的再激活作用[J].广东医学,2007,28(10):1699-1701. 被引量:1
  • 4Said ES, E1 Husseiny NM, Mosaad NA. Evaluation of serum level of tumor necrosis factor receptor II in hepatitis C virus ( genotype 4 ) - infected middle - aged men with and without diabetes and its complications in Egypt: a pilot study[J]. J Investig Med, 2011, 59(8) : 1276 - 1279.
  • 5Morlat P, Pereira E, Clayette P, et al. Early evolution of plasma soluble TNF - alpha p75 receptor as a marker of progression in treated HIVinfected patients [ J]. AIDS Res Hum Retroviruses, 2008, 24(11) : 1383 -1389.
  • 6Sun R, Zhang Y, Lv Q, et al. Toll - like receptor 3 ( TLR3 ) in- duces apoptosis via death receptors and mitochondria by up - regu- lating the transactivating p63 isoform alpha (TAP63alpha) [ J ~. J Biol Chem, 2011, 286 ( 18 ) : 15918 - 15928.
  • 7Kawai T, Akira S. Regulation of innate immune signalling path- ways by the tripartite motif (TRIM) family proteins [ J~. EMBO Mol Med, 2011, 3(9) : 513 -527.
  • 8McNab FW, Rajsbaum R, Stoye JP, et al. Tripartite-motif pro- teins and innate immune regulation [ J ]. Curt Opin Immunol, 2011,23(1) : 46-56.
  • 9Cochrane TF, Silvestri (,, Mel)owell C,et al. Acute retinal necrosis in the United Kingdom: results of a prospective surveillance study. Eye (Lond) 2012 ;26 ( 3 ) :370-377.
  • 10Yeh S,Suhler EB,Smith J R,et al. Combination systemic and intravitreal antiviral therapy in the management of acute retinal necrosis syndrome. Ophthalmic Surg l~tsers Imaging Retina 2014 ;45 (5) :399-407.

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