摘要
从成骨细胞和破骨细胞来源的同一性,其间存在的生、克、制、化关系,阳性、阴性调控因子,阴阳属性的相对性等方面,阐释骨稳态中成骨细胞、破骨细胞的阴阳属性。认为成骨细胞和破骨细胞在骨稳态内是典型的阴阳关系,成骨细胞及其主导的骨生成属于"阴",破骨细胞及其主导的骨吸收属于"阳",二者动态平衡发挥维持骨稳态的作用。
This paper aims to use the application of Yin-Yang theory in bone remodeling to address the nature of Yin-Yang theory in TCM. Here we propose that osteoblasts( bone-forming cells) and bone formation should be considered Yin,while osteoclasts( bone-resorbing cells) and bone resorption should be regarded as Yang. Moreover,we argue that the Yin-Yang relationship exists between osteoblasts and osteoclasts,and we conclude that the relationship between osteoblasts and osteoclasts as established in contemporary biology reflects the classic Yin-Yang in bone homeostasis. Therefore,the new Yin-Yang concept of osteoblasts and osteoclasts in bone homeostasis may strengthen the basic theory of TCM as well as guide clinical practice.
出处
《上海中医药杂志》
2015年第4期5-10,共6页
Shanghai Journal of Traditional Chinese Medicine
基金
国家重点基础研究发展计划("973"计划)项目(2010CB530400)
教育部"长江学者特聘教授计划"项目[教人(2009)17]
上海市卫生局"重中之重"临床医学中心建设计划项目[沪卫科教(2012)052]
国家自然科学基金项目(81330085
81102606
81102605
81202708
81173278
81102851
81072831
81373666)
国家中医临床研究基地龙医学者
龙医团队计划项目(LYTD-23)
上海市科委"扬帆计划"项目(15YF1412200)
中国博士后自然科学基金项目(2011M500620)
上海中医药大学附属龙华医院自然科学基金项目(14YR03)
关键词
骨稳态
成骨细胞
破骨细胞
阴阳学说
bone homeostasis
osteoblast
osteoclast
Yin-Yang theory