骨稳态中成骨细胞与破骨细胞的阴阳属性

Yin-Yang property of osteoblast and osteoclast in bone homeostasis

从成骨细胞和破骨细胞来源的同一性,其间存在的生、克、制、化关系,阳性、阴性调控因子,阴阳属性的相对性等方面,阐释骨稳态中成骨细胞、破骨细胞的阴阳属性。认为成骨细胞和破骨细胞在骨稳态内是典型的阴阳关系,成骨细胞及其主导的骨生成属于"阴",破骨细胞及其主导的骨吸收属于"阳",二者动态平衡发挥维持骨稳态的作用。

This paper aims to use the application of Yin-Yang theory in bone remodeling to address the nature of Yin-Yang theory in TCM. Here we propose that osteoblasts（ bone-forming cells） and bone formation should be considered Yin,while osteoclasts（ bone-resorbing cells） and bone resorption should be regarded as Yang. Moreover,we argue that the Yin-Yang relationship exists between osteoblasts and osteoclasts,and we conclude that the relationship between osteoblasts and osteoclasts as established in contemporary biology reflects the classic Yin-Yang in bone homeostasis. Therefore,the new Yin-Yang concept of osteoblasts and osteoclasts in bone homeostasis may strengthen the basic theory of TCM as well as guide clinical practice.