斯氏狸殖吸虫在大鼠体内多部位寄生与宿主转换的实验研究

STUDY ON POLYORGANOTROPISM AND HOST TRANSFER OF PAGVMOGONIMVS SKRJABINl IN RAT

斯氏狸殖吸虫囊蚴经口感染大鼠23d,从体腔、肺、肝、肌肉等部位均检出虫体,57.5％于肌肉,23.8％于肝脏。40d后,除肌肉中的虫体,其它部位检出的虫体均有不同程度的发育。60d后,大鼠的肺、肝、纵隔、腹后壁等处,均有虫囊形成。90d时,85.0％虫体成熟。将大鼠体内40d虫龄发育较小的童虫60条,经口感染另一大鼠,70d时在其肺部查见6个虫囊,9条虫,其中4条成熟含卵。结果表明,斯氏狸殖吸虫在大鼠体内多部位寄生且能发育成熟;发育较小的童虫在大鼠间宿主转换后,部分虫体亦可进一步发育而成熟。

40 days after oral infection of rat with metacercariae of Pagumogonimus skrjabini, a few worms matured sexually in the abdominal cavity or worm-cysts formed in the lungs, while juveniles were detected in the muscles.60-90 days after infection, worm-cysts can not only be detected in the lungs, but also in the liver, mediastinum and abdominal wall, with matured or prematured worms and eggs. It is suggested that P. skrjabini could mature in rat and showed a phenomenon of polyor-ganotropism.By means of host-transfer with small juveniles, a part of them migrated to the lungs and matured, but the worms detected in muscles were still stunted (Figs. 1-4) .