药物过量性头痛的研究进展

Update of medication-overuse headache

药物过量性头痛(MOH)是一种常见的与药物过量使用相关的慢性继发性头痛。MOH不仅造成患者身心痛苦,严重影响患者的工作、学习及生活质量,同时也给社会带来巨大的经济负担。MOH对患者生活质量的影响程度比发作性头痛更为严重,致残程度也高于发作性头痛。近年来MOH引起了各国学者越来越多的关注,取得了许多重要的研究成果,本文就MOH的流行病学及临床特点、病理生理学机制、影像学表现、治疗等方面的研究进行综述。

Medication-overuse headache（MOH） is a type of common chronic and secondary headache that is associated with medication overuse. It can not only make patients feel painful both physically and mentally, but also decrease greatly quality of life and work or study of patients and give a high economic burden on society. The quality of life of patients with MOH is poorer than patients with episodic headache and their disability scores are higher than those with episodic headache. In recent years,researchers have paid more attention on MOH and have obtained many achievements. In this review, the epidemiological and clinical features, pathophysiological pathogenesis, imaging findings and therapeutic explorations of this disorder were summarized.