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骨髓增生异常综合征细胞系的研究进展 被引量：2

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摘要 骨髓增生异常综合征（MDS）是一组多步骤累及多基因异常变化而导致的具有高度异质性的造血系统恶性克隆性疾病。主要表现为骨髓髓系细胞一系或多系发育异常，无效造血导致难治性贫血或全血细胞减少及演变为急性髓系白血病风险增高[1]。2008年WHO血液肿瘤分类系统将MDS列为五类主要髓系肿瘤之一。
作者 王倩 许小平
机构地区 复旦大学附属华山医院血液科
出处 《中华医学杂志》 CAS CSCD 北大核心 2015年第12期951-954,共4页 National Medical Journal of China
基金 国家科技重大专项子课题（2012XZ09303004-D01） 国家自然科学基金（81070404、81100389）
关键词 骨髓增生异常综合征 细胞系 恶性克隆性疾病 急性髓系白血病 全血细胞减少 难治性贫血 造血系统 基因异常
分类号 R551.3 [医药卫生—血液循环系统疾病]
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参考文献32

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中华医学杂志
2015年 第12期

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